Starting today, Amazon EC2 I3en instances are available in the US East (Ohio), Asia Pacific (Tokyo), Europe (Frankfurt) AWS regions, and in additional Availability Zones (AZs) in the US East (N. Virginia) AWS Region. I3en global availability now includes the Asia Pacific (Tokyo), Europe (Frankfurt, Ireland), US East (N. Virginia, Ohio), and US West (Oregon) AWS regions. 

from Recent Announcements https://aws.amazon.com/about-aws/whats-new/2019/06/amazon-ec2-i3en-instances-available-in-additional-aws-regions/